摘要
Purpose: To report the effect of a single dose of oxytocin on ejaculation time and seminal parameters.
Methods: The prospective randomized clinical study was performed at a private assisted reproduction technology center and included 103 consecutive healthy men (semen donors or husbands of IVF patients). Oxytocin (16 IU) were administered intranasally to 49 subjects, randomly assigned to the study group just before masturbation to ejaculation. The time needed for ejaculation as well as the semen parameters was recorded according to the WHO standards, and compared to the control group of 54 subjects with no prior oxytocin treatment.
Results: No significant difference was noted between the two groups concerning ejaculation time and semen parameters.
Conclusions: Although the administration of oxytocin stimulates sexual behavior and performance in mammalian species, our data indicate that oxytocin has no detectable effect on ejaculation time and seminal parameters after intranasal application in normal, healthy men.
摘要译文
目的：报告单次剂量的催产素对射精时间和精液参数的效果。编制方法：在一个私人辅助生殖技术中心进行的前瞻性随机对照临床研究，其中包括103个连续的健康男性（精液捐赠者或IVF患者的丈夫）。催产素（16 IU）滴鼻给药49例，随机分为研究组只是自慰射精前。根据WHO标准所需射精以及精液参数的时间被记录，并与54受试者没有预先的催产素治疗的对照组。结果：没有显著差异注意到有关射精的时间和精液参数两组。结论：虽然催产素的管理刺激在哺乳动物的性行为和性能，我们的数据表明，催产素后具有正常，健康男性鼻内对射精时间和精液参数没有可察觉的影响。
Katharina Walch [1] Ruth Eder [1] Andreas Schindler [2] Wilfried Feichtinger [1]. The Effect of Single-Dose Oxytocin Application on Time to Ejaculation and Seminal Parameters in Men[J]. Journal of Assisted Reproduction and Genetics, 2001,18(12): 655-659